„Biotyki” – co wiemy w 2021 roku? / „Biotics” – what is known in 2021?
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Abstract:
A balanced gut microbiota is crucial for health. Conversely, an altered gut microbiota composition and/or activity (dysbiosis) contributes to diseases. There
is an interest in the microbiota modifications. The article summarizes major consensus papers developed by the International Scientific Association for
Probiotics and Prebiotics (ISAPP) on biotics, i.e., probiotics, prebiotics, synbiotics, and postbiotics. The aim is to help making rational decisions regarding
their use. Apart from microbiota, many other factors affect health and contribute to diseases. Thus, one should have realistic expectations regarding
biotics. None of them will act as a panacea. While deciding on a specific “biotic” it is best to recommend the use of only those with documented efficacy
and safety and to use a regimen (dose and formulation, duration of treatment) proven to be effective in well-designed trials for the same indication, informing
about the expected effect size. This will allow patients (or their caregivers) to decide whether the anticipated benefits are in line with their expectations
and worth the costs incurred.
Standardy Medyczne/Pediatria 2021 T. 18 437-446
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